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Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.

Abstract:

We have identified a Drosophila gene, Dror, which encodes a putative receptor tyrosine kinase (RTK) and maps to cytological location 31B/C on the second chromosome. In embryos, this gene is expressed specifically in the developing nervous system. The Dror protein appears to be a homolog of two human RTKs, Ror1 and Ror2. Dror and Ror1 proteins share 36% amino acid identity in their extracellular domains and 61% identity in their catalytic tyrosine kinase (TK) domains. Ror1 and Ror2 were origin...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.90.15.7109

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
90
Issue:
15
Pages:
7109-7113
Publication date:
1993-08-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:6a5a7b16-45b2-4dfd-8d32-3659d5b5bd89
Source identifiers:
113935
Local pid:
pubs:113935

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