- Abstract:
-
We have identified a Drosophila gene, Dror, which encodes a putative receptor tyrosine kinase (RTK) and maps to cytological location 31B/C on the second chromosome. In embryos, this gene is expressed specifically in the developing nervous system. The Dror protein appears to be a homolog of two human RTKs, Ror1 and Ror2. Dror and Ror1 proteins share 36% amino acid identity in their extracellular domains and 61% identity in their catalytic tyrosine kinase (TK) domains. Ror1 and Ror2 were origin...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1073/pnas.90.15.7109
-
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- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 90
- Issue:
- 15
- Pages:
- 7109-7113
- Publication date:
- 1993-08-05
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- URN:
-
uuid:6a5a7b16-45b2-4dfd-8d32-3659d5b5bd89
- Source identifiers:
-
113935
- Local pid:
- pubs:113935
- Copyright date:
- 1993
Journal article
Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.
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