Journal article
Structural basis for reversible photoswitching in Dronpa.
- Abstract:
-
Dronpa is a novel GFP-like fluorescent protein with exceptional light-controlled switching properties. It may be reversibly switched between a fluorescent on-state and a nonfluorescent off-state by irradiation with light. To elucidate the molecular basis of the switching mechanism, we generated reversibly switchable Dronpa protein crystals. Using these crystals we determined the elusive dark-state structure of Dronpa at 1.95-A resolution. We found that the photoswitching results in a cis-tran...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.0700629104
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Authors
Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 104
- Issue:
- 32
- Pages:
- 13005-13009
- Publication date:
- 2007-08-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
222175
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:222175
- UUID:
-
uuid:6a4e94f3-1181-4ee7-a372-5d6000c6f20c
- Local pid:
- pubs:222175
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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