Journal article
Architecture of the major component of the type III secretion system export apparatus.
- Abstract:
-
Type III secretion systems (T3SSs) are bacterial membrane-embedded nanomachines designed to export specifically targeted proteins from the bacterial cytoplasm. Secretion through T3SS is governed by a subset of inner membrane proteins termed the 'export apparatus'. We show that a key member of the Shigella flexneri export apparatus, MxiA, assembles into a ring essential for secretion in vivo. The ring-forming interfaces are well-conserved in both nonflagellar and flagellar homologs, implying t...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/nsmb.2452
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Authors
Bibliographic Details
- Journal:
- Nature structural and molecular biology
- Volume:
- 20
- Issue:
- 1
- Pages:
- 99-104
- Publication date:
- 2013-01-01
- DOI:
- EISSN:
-
1545-9985
- ISSN:
-
1545-9993
- Source identifiers:
-
366134
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:366134
- UUID:
-
uuid:6a304eb1-f3d2-4742-8172-8665f5274589
- Local pid:
- pubs:366134
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2013
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