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An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).

Abstract:

OBJECTIVE: To determine the efficacy and safety of oral dihydroartemisinin-piperaquine (DP, Artekin) in the treatment of uncomplicated Plasmodium falciparum malaria in southern Laos. METHODS: An open, randomized clinical trial of oral artesunate-mefloquine (AM) vs. DP in 220 patients with acute uncomplicated falciparum malaria in Savannakhet Province, Laos. RESULTS: The 42-day cure rates (95% CI), as determined by survival analysis and adjusted for reinfection, were excellent and similar for ...

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Publication status:
Published

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Journal:
Tropical medicine and international health : TM and IH
Volume:
11
Issue:
8
Pages:
1157-1165
Publication date:
2006-08-05
DOI:
EISSN:
1365-3156
ISSN:
1360-2276
URN:
uuid:6a1b1b6b-12ce-46e0-bb23-b59463dd5a58
Source identifiers:
27195
Local pid:
pubs:27195

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