The role of photon scattering in optical signal distortion during arrhythmia and defibrillation.

Journal article

Optical mapping of arrhythmias and defibrillation provides important insights; however, a limitation of the technique is signal distortion due to photon scattering. The goal of this experimental/simulation study is to investigate the role of three-dimensional photon scattering in optical signal distortion during ventricular tachycardia (VT) and defibrillation. A three-dimensional realistic bidomain rabbit ventricular model was combined with a model of photon transport. Shocks were applied via...

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Authors: Bishop, M; Rodriguez, B; Qu, F; Efimov, I; Gavaghan, D

• Publication status: Published
• Journal: Biophysical journal
• Volume: 93
• Issue: 10
• Pages: 3714-3726
• Publication date: 2007-11-01
• DOI: 10.1529/biophysj.107.110981
• EISSN: 1542-0086
• ISSN: 0006-3495
• Language: English
• Keywords: Photons; Software; Membrane Potentials; Perfusion; Heart Conduction System; Heart; Time Factors; Pericardium; Computer Simulation; Tachycardia, Ventricular; Arrhythmias, Cardiac; Animals; Electrodes; Action Potentials; Scattering, Radiation; Electric Countershock; Rabbits