- Abstract:
-
Instances in which natural selection maintains genetic variation in a population over millions of years are thought to be extremely rare. We conducted a genome-wide scan for long-lived balancing selection by looking for combinations of SNPs shared between humans and chimpanzees. In addition to the major histocompatibility complex, we identified 125 regions in which the same haplotypes are segregating in the two species, all but two of which are noncoding. In six cases, there is evidence for a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1126/science.1234070
-
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- Publisher:
- American Association for the Advancement of Science
- Journal:
- Science (New York, N.Y.)
- Volume:
- 339
- Issue:
- 6127
- Pages:
- 1578-1582
- Publication date:
- 2013-03-05
- DOI:
- EISSN:
-
1095-9203
- ISSN:
-
0036-8075
- URN:
-
uuid:69f1d764-3d93-4cff-91b9-201b450fe69f
- Source identifiers:
-
388180
- Local pid:
- pubs:388180
- Copyright date:
- 2013
Journal article
Multiple instances of ancient balancing selection shared between humans and chimpanzees.
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