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Journal article

The pancreatic β cell: Recent insights from human genetics

Abstract:

Diabetes mellitus is a metabolic disease characterised by relative or absolute pancreatic β cell dysfunction. Genetic variants implicated in disease risk can be identified by studying affected individuals. To understand the mechanisms driving genetic associations, variants must be translated through causative transcripts to biological insights. Studies into the genetic basis of Mendelian forms of diabetes have successfully identified genes involved in both β cell function and pancreatic devel...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tem.2014.05.001

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More from this funder
Name:
Wellcome Trust
Funding agency for:
Gloyn, A
Publisher:
Cell Press
Journal:
Trends in Endocrinology and Metabolism More from this journal
Volume:
25
Issue:
8
Pages:
425-434
Publication date:
2014-08-01
DOI:
EISSN:
1879-3061
ISSN:
1043-2760
Language:
English
Keywords:
UUID:
uuid:69ea83f6-4277-45ee-bccf-05be321f8be4
Local pid:
pubs:478220
Source identifiers:
478220
Deposit date:
2014-08-21

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