Emergency of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child
Objective: The use of antiretrovirals (ARV) during pregnancy has drastically reduced the rate of the human immunodeficiency virus perinatal transmission (MTCT). As a consequence of widespread ARV use, transmission of drug resistant strains from mothers to their babies is increasing. Ultra-sensitive PCR techniques have permitted the quantification of minority viral populations, but little is known about the transmission of drug-resistant HIV-1 minority population in the setting of MTCT. Method...Expand abstract
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- Peer review status:
- Peer reviewed
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- Copyright holder:
- Machado et al.
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- Citation: Machado, E. S. et al. (2009). 'Emergency of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child', PLoS ONE 4(3), e4806. [Available at http://www.plosone.org]. © 2009 Machado et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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