Journal article icon

Journal article

Emergency of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child

Abstract:

Objective: The use of antiretrovirals (ARV) during pregnancy has drastically reduced the rate of the human immunodeficiency virus perinatal transmission (MTCT). As a consequence of widespread ARV use, transmission of drug resistant strains from mothers to their babies is increasing. Ultra-sensitive PCR techniques have permitted the quantification of minority viral populations, but little is known about the transmission of drug-resistant HIV-1 minority population in the setting of MTCT. Method...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
"Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil", "Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"
Role:
Author
More by this author
Institution:
"Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"
Role:
Author
More by this author
Institution:
"NCI-Frederick, Maryland, USA", "SAIC-Frederick, Maryland, USA"
Department:
Basic Science Program
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
"Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"
Role:
Author
More from this funder
Name:
National Cancer Institute
Grant:
N01-CO012400
More from this funder
Name:
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
Funding agency for:
Machado, E
More from this funder
Name:
Brazilian Ministry of Health
More from this funder
Name:
National Institutes of Health
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
4
Issue:
3
Article number:
e4806
Publication date:
2009-03-01
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Subjects:
UUID:
uuid:69c7aa43-98e5-473a-a837-b42e845d29ea
Local pid:
ora:2830
Deposit date:
2009-06-15

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP