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Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.

Abstract:

Erythrocyte invasion by Plasmodium falciparum is central to the pathogenesis of malaria. Invasion requires a series of extracellular recognition events between erythrocyte receptors and ligands on the merozoite, the invasive form of the parasite. None of the few known receptor-ligand interactions involved are required in all parasite strains, indicating that the parasite is able to access multiple redundant invasion pathways. Here, we show that we have identified a receptor-ligand pair that i...

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Publication status:
Published

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Publisher copy:
10.1038/nature10606

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Journal:
Nature More from this journal
Volume:
480
Issue:
7378
Pages:
534-537
Publication date:
2011-12-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Language:
English
Keywords:
Pubs id:
pubs:239937
UUID:
uuid:69b6c91a-c299-4281-a562-6e1ecbd318cc
Local pid:
pubs:239937
Source identifiers:
239937
Deposit date:
2012-12-19

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