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Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis--a clinical study using myocardial T1-mapping and extracellular volume quantification.

Abstract:

BACKGROUND: Systemic sclerosis (SSc) is characterised by multi-organ tissue fibrosis including the myocardium. Diffuse myocardial fibrosis can be detected non-invasively by T1 and extracellular volume (ECV) quantification, while focal myocardial inflammation and fibrosis may be detected by T2-weighted and late gadolinium enhancement (LGE), respectively, using cardiovascular magnetic resonance (CMR). We hypothesised that multiparametric CMR can detect subclinical myocardial involvement in pati...

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Publication status:
Published

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Publisher copy:
10.1186/1532-429X-16-21

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance More from this journal
Volume:
16
Pages:
21
Publication date:
2014-01-01
DOI:
EISSN:
1532-429X
ISSN:
1097-6647

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