Myocardial microstructure and its role in propagation dynamics

Thesis

Computational modelling and simulation, in close interaction with experiments, has provided invaluable insight into the biochemical, mechanical and electrophysiological function and dysfunction of the heart. However, limitations in imaging techniques and computing resources have precluded the analysis of tissue architecture near the cellular scale and the effect of this architecture on cardiac function.

It is the wider aim of this thesis to develop a framework to characterise cardia...

Expand abstract

Authors: Gibb, M; Matthew Gibb

• Publication date: 2012
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: registration; computational biology; medical imaging
• Subjects: mathematical modeling (engineering); bioinformatics (technology); cardiovascular disease; medical Engineering; biomedical engineering; image understanding