Journal article
Host selection of microbiota via differential adhesion
- Abstract:
-
The host epithelium is the critical interface with microbial communities, but the mechanisms by which the host regulates these communities are poorly understood. Here we develop the hypothesis that hosts use differential adhesion to select for and against particular members of their microbiota. We use an established computational, individual-based model to study the impact of host factors that regulate adhesion at the epithelial surface. Our simulations predict that host-mediated adhesion can...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
McLoughlin, K
Smith, A
Grant:
BB/J014427/1
OD0221
Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Cell Host and Microbe Journal website
- Volume:
- 19
- Issue:
- 4
- Pages:
- 550-559
- Publication date:
- 2016-03-24
- Acceptance date:
- 2016-02-26
- DOI:
- EISSN:
-
1934-6069
- ISSN:
-
1931-3128
Item Description
- Language:
- English
- Pubs id:
-
pubs:616802
- UUID:
-
uuid:6996d2e2-ca29-4038-a268-8c82e9adc5d0
- Local pid:
- pubs:616802
- Source identifiers:
-
616802
- Deposit date:
- 2016-05-09
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2016
- Notes:
- ©2016 Elsevier Inc. This is the accepted manuscript version of the article. The final version is available online from Elsevier (Cell Press) at: [10.1016/j.chom.2016.02.021].
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