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FLO1 is a variable green beard gene that drives biofilm-like cooperation in budding yeast.

Abstract:

The budding yeast, Saccharomyces cerevisiae, has emerged as an archetype of eukaryotic cell biology. Here we show that S. cerevisiae is also a model for the evolution of cooperative behavior by revisiting flocculation, a self-adherence phenotype lacking in most laboratory strains. Expression of the gene FLO1 in the laboratory strain S288C restores flocculation, an altered physiological state, reminiscent of bacterial biofilms. Flocculation protects the FLO1 expressing cells from multiple stre...

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Publication status:
Published

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Publisher copy:
10.1016/j.cell.2008.09.037

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Journal:
Cell More from this journal
Volume:
135
Issue:
4
Pages:
726-737
Publication date:
2008-11-01
DOI:
EISSN:
1097-4172
ISSN:
0092-8674

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