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Journal article

Harmonized genome wide typing of tubercle bacilli using a web-based gene-by-gene nomenclature system

Abstract:

Background

Global tuberculosis (TB) control is challenged by uncontrolled transmission of Mycobacteriumtuberculosis complex (Mtbc) strains, esp. of multidrug (MDR) or extensively resistant (XDR) variants. Precise analysis of transmission networks is the basis to trace outbreak M/XDR clones and improve TB control. However, classical genotyping tools lack discriminatory power due to the high similarity of strains of particular successful lineages, e.g. Beijing or outbreak strains. ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More from this funder
Name:
Seventh Framework Programme
Grant:
FP7-278864-2
More from this funder
Name:
Medical Research Council
Grant:
MR/J011398/1
More from this funder
Name:
National Institute for Health Research
Grant:
CL-2015-13-003
More from this funder
Name:
German Center for Infection Research
Publisher:
Elsevier
Journal:
EBioMedicine More from this journal
Volume:
34
Pages:
131-138
Publication date:
2018-08-13
Acceptance date:
2018-07-20
DOI:
EISSN:
2352-3964
ISSN:
2352-3964
Pmid:
30115606
Language:
English
Keywords:
Pubs id:
pubs:909969
UUID:
uuid:697cd6a7-0523-4c83-be26-2250491aa9bf
Local pid:
pubs:909969
Source identifiers:
909969
Deposit date:
2018-08-28

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