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Journal article

Promoter hyper-methylation of calcium binding proteins S100A6 and S100A2 in human prostate cancer.

Abstract:

BACKGROUND: S100A6 and S100A2 are members of the S100 family of calcium binding proteins, which are down regulated in prostate cancer, however the molecular mechanism(s) underlying their loss of expression is unknown. METHODS: The promoter and exon 1 region of the S100A6 and S100A2 genes was sequenced in bisulfite modified DNA from non-malignant, benign prostatic hyperplasia (BPH), malignant and metastatic prostate tissues and in cell lines. Immunohistochemistry was performed to correlate S1...

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Publication status:
Published

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Publisher copy:
10.1002/pros.20302

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Journal:
Prostate More from this journal
Volume:
65
Issue:
4
Pages:
322-330
Publication date:
2005-12-01
DOI:
EISSN:
1097-0045
ISSN:
0270-4137
Language:
English
Keywords:
Pubs id:
pubs:120664
UUID:
uuid:69773add-09e2-4538-99eb-60ed2e36a0ce
Local pid:
pubs:120664
Source identifiers:
120664
Deposit date:
2012-12-19

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