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Isolated ACTH deficiency with absent response to corticotrophin-releasing factor--41. Evidence for a primary pituitary defect.

Abstract:
An 8-year-old girl presenting in hypoglycaemic coma was shown to have isolated deficiency of adrenocorticotrophic hormone (ACTH) secretion. Failure to secrete ACTH in response to intravenous administration of synthetic ovine corticotrophin-releasing factor (CRF-41) suggests that this disorder was due to a primary pituitary defect, rather than of hypothalamic origin.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
Journal:
Acta paediatrica Scandinavica
Volume:
80
Issue:
2
Pages:
259-261
Publication date:
1991-02-05
DOI:
EISSN:
1651-2227
ISSN:
0001-656X
URN:
uuid:696662a0-2e21-448b-ae7e-5f15c55cec50
Source identifiers:
138401
Local pid:
pubs:138401

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