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Influence of methodological and patient factors on serum NMDAR IgG antibody detection in psychotic disorders: a meta-analysis of cross-sectional and case-control studies

Abstract:

Background: Antibodies targeting the N-methyl-D-aspartate receptor (NMDAR) have been detected in patients with psychosis. However, studies measuring the IgG subclass in serum have provided variable estimates of prevalence, and it is unclear whether these antibodies are more common in patients than controls. Because these inconsistencies could be due to methodological approaches and patient characteristics, we aimed to investigate the effect of these factors on heterogeneit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2215-0366(20)30432-6

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Lancet Psychiatry Journal website
Volume:
8
Issue:
2
Pages:
109-120
Publication date:
2020-12-21
Acceptance date:
2020-09-23
DOI:
EISSN:
2215-0374
ISSN:
2215-0366
Language:
English
Keywords:
Pubs id:
1133433
Local pid:
pubs:1133433
Deposit date:
2020-09-24

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