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Phase-dependence of response curves to deep brain stimulation and their relationship: from essential tremor patient data to a Wilson–Cowan model

Abstract:

Essential tremor manifests predominantly as a tremor of the upper limbs. One therapy option is high-frequency deep brain stimulation, which continuously delivers electrical stimulation to the ventral intermediate nucleus of the thalamus at about 130 Hz. Constant stimulation can lead to side effects, it is therefore desirable to find ways to stimulate less while maintaining clinical efficacy. One strategy, phase-locked deep brain stimulation, consists of stimulating according to the phase of t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13408-020-00081-0

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
Brasenose College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0002-5201-3044
Publisher:
Springer Nature
Journal:
Journal of Mathematical Neuroscience More from this journal
Volume:
10
Issue:
1
Article number:
4
Publication date:
2020-03-30
Acceptance date:
2020-03-12
DOI:
EISSN:
2190-8567
Language:
English
Keywords:
Pubs id:
1098202
Local pid:
pubs:1098202
Deposit date:
2020-04-02

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