Journal article
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis
- Abstract:
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Background Periodontitis (PD) is a known risk factor for rheumatoid arthritis (RA) and there is increasing evidence that the link between the two diseases is due to citrullination by the unique bacterial peptidylarginine deiminase (PAD) enzyme expressed by periodontal pathogen Pophyromonas gingivalis (PPAD). However, the precise mechanism by which PPAD could generate potentially immunogenic peptides has remained controversial due to lack of information about the structural and catalytic mecha...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 1.9MB)
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- Publisher copy:
- 10.1136/annrheumdis-2015-207656
Authors
Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- Annals of the Rheumatic Diseases Journal website
- Volume:
- 75
- Issue:
- 6
- Pages:
- 1255-1261
- Publication date:
- 2015-07-24
- Acceptance date:
- 2015-07-06
- DOI:
- EISSN:
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1468-2060
- ISSN:
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0003-4967
- Pmid:
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26209657
Item Description
- Keywords:
- Pubs id:
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pubs:720788
- UUID:
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uuid:6944c2a9-e1c6-4a1f-82b8-ea85eb3b80ee
- Local pid:
- pubs:720788
- Source identifiers:
-
720788
- Deposit date:
- 2017-08-18
Terms of use
- Copyright holder:
- Montgomery et al
- Copyright date:
- 2015
- Notes:
- Copyright 2016 © The Authors. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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