Journal article
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes.
- Abstract:
-
OBJECTIVE: The ATP-dependent K+-channel (K(ATP)) is critical for glucose sensing and normal glucagon and insulin secretion from pancreatic endocrine alpha- and beta-cells. Gastrointestinal endocrine L- and K-cells are also glucose-sensing cells secreting glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotrophic polypeptide (GIP) respectively. The aims of this study were to 1) investigate the expression and co-localisation of the K(ATP) channel subunits, Kir6.2 and SUR1, in human ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1530/eje-06-0756
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Bibliographic Details
- Journal:
- European journal of endocrinology / European Federation of Endocrine Societies
- Volume:
- 156
- Issue:
- 6
- Pages:
- 663-671
- Publication date:
- 2007-06-01
- DOI:
- EISSN:
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1479-683X
- ISSN:
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0804-4643
- Source identifiers:
-
16274
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:16274
- UUID:
-
uuid:69368933-b92d-4415-ac2e-7c2d073cedff
- Local pid:
- pubs:16274
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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