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Identification of a population of placental alkaline phosphatase negative syncytiotrophoblast exosomes using a multiplex exosome kit

Abstract:
The placenta plays an important role in pathogenesis of pregnancy related disease such as gestational diabetes and preeclampsia. Syncytiotrophoblast derived exosomes (STBEX) are released into the maternal circulation and have been suggested as novel biomarkers to predict disease. Placental alkaline phosphatase (PLAP) has been used as a specific marker to select STBEX. We wondered if there are STBEX that do not express PLAP.
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Women’s & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Women’s & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Women’s & Reproductive Health
Sub department:
Women's & Reproductive Health
Department:
Oxford, MSD, Womens & Reproductive Health
Role:
Author
ORCID:
0000-0002-6012-2574
Publisher:
Elsevier
Host title:
Placenta
Journal:
2018 International Federation of Placenta Associations Meeting (IFPA 2018) More from this journal
Volume:
69
Pages:
E90
Publication date:
2018-09-10
DOI:
EISSN:
1532-3102
ISSN:
0143-4004
Pubs id:
pubs:921710
UUID:
uuid:691d3185-a7f7-4367-ba0e-ad07900b1d3b
Local pid:
pubs:921710
Source identifiers:
921710
Deposit date:
2018-10-02

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