Journal article : Review
Recent advances in lipopolysaccharide-based glycoconjugate vaccines
- Abstract:
-
Introduction The public health burden caused by pathogenic Gram-negative bacteria is increasingly prominent due to antimicrobial resistance. The surface carbohydrates are potential antigens for vaccines against Gram-negative bacteria. The enhanced immunogenicity of the O-specific polysaccharide (O-SP) moiety of LPS when coupled to a carrier protein may protect against bacterial pathogens. However, because of the toxic lipid A moiety and relatively high costs of O-SP isolation... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
NIHR Oxford Biomedical Research Centre
More from this funder
Bibliographic Details
- Publisher:
- Taylor and Francis Publisher's website
- Journal:
- Expert Review of Vaccines Journal website
- Volume:
- 20
- Issue:
- 12
- Pages:
- 1515-1538
- Publication date:
- 2021-09-22
- Acceptance date:
- 2021-09-21
- DOI:
- EISSN:
-
1744-8395
- ISSN:
-
1476-0584
- Pmid:
-
34550840
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1210278
- Local pid:
- pubs:1210278
- Deposit date:
- 2021-12-18
Terms of use
- Copyright holder:
- Zhu et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record