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Journal article

T regulatory cells and the control of alloimmunity: from characterisation to clinical application.

Abstract:

T regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance. Recent findings in experimental transplant models combined with the development of functional reporter mice have opened new avenues to study Treg biology and their therapeutic potential. In particular, recent advances in understanding Treg function and lineage stability revealed unexpected plasticity of this lineage. Nevertheless, pre-clinical and pilot clinical trials using Treg cell...

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Publication status:
Published

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Publisher copy:
10.1016/j.coi.2010.08.011

Authors


Wieckiewicz, J More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
Current opinion in immunology
Volume:
22
Issue:
5
Pages:
662-668
Publication date:
2010-10-05
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
URN:
uuid:6912867d-b72f-425a-b55e-1b8bb7903d59
Source identifiers:
135997
Local pid:
pubs:135997

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