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Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases.

Abstract:
Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to sensitive responsive photoluminescent probes for protein kinase CK2 that emitted red light with a long (microsecond-scale) decay time upon excitation of the probes with a pulse of near-UV light.
Publication status:
Published

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Publisher copy:
10.1039/c3cc49198f

Authors


Ekambaram, R More by this author
Enkvist, E More by this author
Manoharan, G More by this author
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Journal:
Chemical communications (Cambridge, England)
Volume:
50
Issue:
31
Pages:
4096-4098
Publication date:
2014-04-05
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:69104dae-005c-4788-981e-bce30c9fe17a
Source identifiers:
462841
Local pid:
pubs:462841

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