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What is a transcriptional burst?

Abstract:

The idea that gene activity can be discontinuous will not surprise many biologists – many genes are restricted in when and where they can be expressed. Yet during the past 15 years, a collection of observations compiled under the umbrella term ‘transcriptional bursting’ has received considerable interest. Direct visualization of the dynamics of discontinuous transcription has expanded our understanding of basic transcriptional mechanisms and their regulation, and provides a real-time readout ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tig.2020.01.003

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
Publisher:
Elsevier
Journal:
Trends in Genetics More from this journal
Volume:
36
Issue:
4
Pages:
288-297
Publication date:
2020-02-05
DOI:
EISSN:
1362-4555
ISSN:
0168-9525
Language:
English
Keywords:
Pubs id:
1102755
Local pid:
pubs:1102755
Deposit date:
2020-05-04

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