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Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials.

Abstract:

BACKGROUND: Erythropoiesis-stimulating agents reduce anaemia in patients with cancer and could improve their quality of life, but these drugs might increase mortality. We therefore did a meta-analysis of randomised controlled trials in which these drugs plus red blood cell transfusions were compared with transfusion alone for prophylaxis or treatment of anaemia in patients with cancer. METHODS: Data for patients treated with epoetin alfa, epoetin beta, or darbepoetin alfa were obtained and a...

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Publication status:
Published

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Journal:
Lancet More from this journal
Volume:
373
Issue:
9674
Pages:
1532-1542
Publication date:
2009-05-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736

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