- Abstract:
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In the heart compartmentalisation of cAMP/protein kinase A (PKA) signalling is necessary to achieve a specific functional outcome in response to different hormonal stimuli. Chronic exposure to catecholamines is known to be detrimental to the heart and disrupted compartmentalisation of cAMP signalling has been associated to heart disease. However, in most cases it remains unclear whether altered local cAMP signalling is an adaptive response, a consequence of the disease or whether it contribut...
Expand abstract - Publication status:
- In press
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 2.0mb)
-
- Publisher copy:
- 10.1016/j.cellsig.2015.10.003
-
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- Grant:
- PG/10/75/28537; RG/12/3/29423; PG/15/5/31110
- Publisher:
- Elsevier Publisher's website
- Journal:
- Cellular Signalling Journal website
- Publication date:
- 2015-10-05
- DOI:
- ISSN:
-
0898-6568
- URN:
-
uuid:68e5fbbc-14a2-4df2-91e1-04f5d5a2270e
- Source identifiers:
-
574959
- Local pid:
- pubs:574959
- Copyright holder:
- Fields et al.
- Copyright date:
- 2015
- Notes:
- Under a Creative Commons license. Open Access funded by British Heart Foundation.
Journal article
Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes
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+ British Heart Foundation
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