Journal article icon

Journal article

Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.

Abstract:

BACKGROUND: Identification of individuals latently infected with Mycobacterium tuberculosis is an important part of tuberculosis control. The current method, the tuberculin skin test (TST), has poor specificity because of the antigenic cross-reactivity of purified protein derivative (PPD) with M bovis BCG vaccine and environmental mycobacteria. ESAT-6 is a secreted antigen that is highly specific for M tuberculosis complex, but is absent from M bovis BCG. With an enzyme-linked immunospot (ELI...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Journal:
Lancet More from this journal
Volume:
357
Issue:
9273
Pages:
2017-2021
Publication date:
2001-06-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Language:
English
Keywords:
Pubs id:
pubs:31911
UUID:
uuid:68d8aa45-f240-4dd6-83d4-f2e56312e944
Local pid:
pubs:31911
Source identifiers:
31911
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP