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Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction

Abstract:
Plasma concentrations of glucose and insulin were measured in ten patients during the Jarisch-Herxheimer reaction of tetracycline-treated louse-borne relapsing fever. Plasma glucose fell significantly in eight of the ten patients associated with the peak of the reaction, but plasma insulin remained low. Glucoregulation by insulin was therefore normal. This evidence questions the role of macrophage mediator-induced pancreatic insulin release in causing hypoglycaemia in borreliosis or bacterial endotoxicosis. © 1985.

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Authors


Habte-Mlchael, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Warrell, DA More by this author
Wright, DJM More by this author
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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
79
Issue:
1
Pages:
78-79
Publication date:
1985
DOI:
ISSN:
0035-9203
URN:
uuid:68b9d0b5-919c-4bf7-9c06-84e74e7fdb36
Source identifiers:
80096
Local pid:
pubs:80096
Language:
English

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