- Abstract:
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Aberrant rule- and reward-based processes underpin abnormalities of socio-emotional behaviour in major dementias. However, these processes remain poorly characterized. Here we used music to probe rule decoding and reward valuation in patients with frontotemporal dementia (FTD) syndromes and Alzheimer’s disease (AD) relative to healthy age-matched individuals. We created short melodies that were either harmonically resolved (‘finished’) or unresolved (‘unfinished’); the task was to classify ea...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 324.1kb)
-
- Publisher copy:
- 10.1093/scan/nsx140
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Social Cognitive and Affective Neuroscience Journal website
- Volume:
- 13
- Issue:
- 2
- Pages:
- 192–202
- Publication date:
- 2018-02-01
- Acceptance date:
- 2017-11-19
- DOI:
- EISSN:
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1749-5024
- ISSN:
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1749-5016
- Pubs id:
-
pubs:855617
- URN:
-
uri:68af7da7-407c-4462-86cb-5ce56c19538c
- UUID:
-
uuid:68af7da7-407c-4462-86cb-5ce56c19538c
- Local pid:
- pubs:855617
- Language:
- English
- Keywords:
- Copyright holder:
- Clark et.al
- Copyright date:
- 2018
- Notes:
-
© The Authors (2017). Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Journal article
Music models aberrant rule decoding and reward valuation in dementia
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Funding
Alzheimer’s Society
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Wellcome Trust
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NIHR Queen Square Dementia Biomedical Research Unit
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NIHR University College London Hospitals Trust Biomedical Research Centre
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