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Journal article

Music models aberrant rule decoding and reward valuation in dementia

Abstract:

Aberrant rule- and reward-based processes underpin abnormalities of socio-emotional behaviour in major dementias. However, these processes remain poorly characterized. Here we used music to probe rule decoding and reward valuation in patients with frontotemporal dementia (FTD) syndromes and Alzheimer’s disease (AD) relative to healthy age-matched individuals. We created short melodies that were either harmonically resolved (‘finished’) or unresolved (‘unfinished’); the task was to classify ea...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1093/scan/nsx140

Authors


Golden, HL More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Divisional Administration
Nicholas, JM More by this author
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Alzheimer’s Society More from this funder
Wellcome Trust More from this funder
NIHR Queen Square Dementia Biomedical Research Unit More from this funder
NIHR University College London Hospitals Trust Biomedical Research Centre More from this funder
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Publisher:
Oxford University Press Publisher's website
Journal:
Social Cognitive and Affective Neuroscience Journal website
Volume:
13
Issue:
2
Pages:
192–202
Publication date:
2018-02-01
Acceptance date:
2017-11-19
DOI:
EISSN:
1749-5024
ISSN:
1749-5016
Pubs id:
pubs:855617
URN:
uri:68af7da7-407c-4462-86cb-5ce56c19538c
UUID:
uuid:68af7da7-407c-4462-86cb-5ce56c19538c
Local pid:
pubs:855617

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