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Journal article

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)

Abstract:

Genome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to breast cancer risk, we performed a high resolution fine-mapping analysis that involved genotyping 517 SNPs using a custom Illumina iSelect array (iCOGS) followed by imputation of genotypes for 3,134 SNPs in more than 89,000 participants of European ancestry from the Breast Cancer Association Consortium (BCAC). We identified 28 highly correlated co...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/srep32512

Authors


Beesley, J More by this author
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National Cancer Institute NIH More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
6
Pages:
32512
Publication date:
2016-09-07
Acceptance date:
2016-08-03
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
Pubs id:
pubs:642229
URN:
uri:68ad9183-05e7-4385-a3c0-86dc011325fd
UUID:
uuid:68ad9183-05e7-4385-a3c0-86dc011325fd
Local pid:
pubs:642229
Language:
English
Keywords:

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