- Abstract:
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Genome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to breast cancer risk, we performed a high resolution fine-mapping analysis that involved genotyping 517 SNPs using a custom Illumina iSelect array (iCOGS) followed by imputation of genotypes for 3,134 SNPs in more than 89,000 participants of European ancestry from the Breast Cancer Association Consortium (BCAC). We identified 28 highly correlated co...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 992.4kb)
-
- Publisher copy:
- 10.1038/srep32512
-
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- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 6
- Pages:
- 32512
- Publication date:
- 2016-09-07
- Acceptance date:
- 2016-08-03
- DOI:
- EISSN:
-
2045-2322
- ISSN:
-
2045-2322
- Pubs id:
-
pubs:642229
- URN:
-
uri:68ad9183-05e7-4385-a3c0-86dc011325fd
- UUID:
-
uuid:68ad9183-05e7-4385-a3c0-86dc011325fd
- Local pid:
- pubs:642229
- Language:
- English
- Keywords:
- Copyright holder:
- Darabi et al.
- Copyright date:
- 2016
- Notes:
- © The Author(s) 2017. This article has been accepted for publication in Scientific Reports. This work is licensed under a Creative Commons Attribution 4.0 International License.
Journal article
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)
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National Cancer Institute NIH
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