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Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials.

Abstract:

The effects of prophylactic lidocaine hydrochloride on early ventricular fibrillation and death in patients with suspected acute myocardial infarction were investigated in an overview of 14 randomized trials. During follow-up intervals of one to four hours in the trials of intramuscular lidocaine infusion (6961 patients) and 24 to 48 hours in the trials of intravenous lidocaine injection (2194 patients), a total of 103 cases of ventricular fibrillation and 137 deaths were recorded. Overall, a...

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Publication status:
Published

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Publisher copy:
10.1001/jama.260.13.1910

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
Journal:
JAMA
Volume:
260
Issue:
13
Pages:
1910-1916
Publication date:
1988-10-05
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
URN:
uuid:68ab298f-7d5e-49a6-9e76-a7db1840c62f
Source identifiers:
35290
Local pid:
pubs:35290

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