Journal article
Distinct peptide loading pathways for MHC class II molecules associated with alternative Ii chain isoforms.
- Abstract:
-
Mutant mouse strains expressing either p31 or p41 Ii chain appear equally competent with respect to their class II functional activities including Ag presentation and CD4+ T cell development. To further explore possibly divergent roles provided by alternative Ii chain isoforms, we compare class II structure and function in double mutants also carrying a null allele at the H2-DM locus. As for DM mutants expressing wild-type Ii chain, Aalpha(b)Abeta(b) dimers present in DM-deficient mice expres...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 160
- Issue:
- 7
- Pages:
- 3101-3110
- Publication date:
- 1998-04-01
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
17150
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:17150
- UUID:
-
uuid:68aaf050-4e84-4a1e-987d-c7c132c4d729
- Local pid:
- pubs:17150
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1998
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