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Journal article

The Ndc80 complex targets Bod1 to human mitotic kinetochores

Abstract:

Regulation of protein phosphatase activity by endogenous protein inhibitors is an important mechanism to control protein phosphorylation in cells. We recently identified Biorientation defective 1 (Bod1) as a small protein inhibitor of protein phosphatase 2A containing the B56 regulatory subunit (PP2A-B56). This phosphatase controls the amount of phosphorylation of several kinetochore proteins and thus the establishment of load-bearing chromosome-spindle attachments in time for accurate separa...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rsob.170099

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
ORCID:
0000-0002-8819-7287
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Grant:
097945/B/11/Z
095931/Z/11/Z
Publisher:
Royal Society Publisher's website
Journal:
Open Biology Journal website
Volume:
7
Issue:
11
Pages:
170099
Publication date:
2017-11-15
Acceptance date:
2017-10-16
DOI:
EISSN:
2046-2441
Source identifiers:
811415
Keywords:
Pubs id:
pubs:811415
UUID:
uuid:68a746bb-d3d0-4f04-ae2c-3d48254ca650
Local pid:
pubs:811415
Deposit date:
2017-12-16

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