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Journal article

Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen.

Abstract:

The spleen, the largest secondary lymphoid organ, has long been known to play important roles in immunity against blood-borne invaders. Yet how cells migrate within the spleen to ensure fast and effective responses is only now coming to light. Chemokines and oxysterols guide lymphocytes from sites of release at terminal arterioles into the lymphocyte-rich white pulp. Sphingosine-1-phosphate (S1P) and S1P-receptor-1 (S1PR1) promote lymphocyte egress from white to red pulp and back to circulati...

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Publication status:
Published

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Publisher copy:
10.1007/978-3-319-05879-5_5

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Current topics in microbiology and immunology
Volume:
378
Pages:
107-128
Publication date:
2014-01-01
DOI:
ISSN:
0070-217X
Source identifiers:
482806
Language:
English
Keywords:
Pubs id:
pubs:482806
UUID:
uuid:68a1d561-32ed-4115-be5f-1b921f1063e4
Local pid:
pubs:482806
Deposit date:
2014-09-12

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