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Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.

Abstract:

OBJECTIVE: IL2RA/CD25, the gene for interleukin-2 receptor alpha, is emerging as a general susceptibility gene for autoimmune diseases because of its role in the development and function of regulatory T cells and the association of single-nucleotide polymorphisms (SNPs) within this gene with type 1 diabetes mellitus (DM), Graves' disease, rheumatoid arthritis (RA), and multiple sclerosis (MS). The aim of this study was to determine whether SNPs within the IL2RA/CD25 gene are associated with j...

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Publisher copy:
10.1002/art.24187

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Journal:
Arthritis and rheumatism
Volume:
60
Issue:
1
Pages:
251-257
Publication date:
2009-01-05
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:689c93f4-c51d-4b65-8d3c-8ebfc447e673
Source identifiers:
120455
Local pid:
pubs:120455

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