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Journal article

Intracellular antibodies as specific reagents for functional ablation: future therapeutic molecules.

Abstract:

The use of antibodies in medicine and research depends on their specificity and affinity in the recogniton and binding of individual molecules. However, these applications are limited to the extracellular targets. Advances in antibody engineering has allowed the manipulation of the antibody segments containing the antigen-binding regions and generation of small fragments that can be stably expressed in cells. These entities are called intracellular antibodies or intrabodies and have being suc...

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Publisher copy:
10.2174/1566524043360384
Journal:
Current molecular medicine More from this journal
Volume:
4
Issue:
5
Pages:
519-528
Publication date:
2004-08-01
DOI:
EISSN:
1875-5666
ISSN:
1566-5240
Language:
English
Keywords:
Pubs id:
pubs:324273
UUID:
uuid:689bfb40-d45f-4135-99aa-13653d6cc548
Local pid:
pubs:324273
Source identifiers:
324273
Deposit date:
2013-11-16

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