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Journal article

Myelin water imaging reflects clinical variability in multiple sclerosis.

Abstract:

Whilst MRI is routinely used for the assessment and diagnosis of multiple sclerosis, there is poor correspondence between clinical disability in primary progressive multiple sclerosis (PPMS) patients and conventional MRI markers of disease activity (e.g., number of enhancing lesions). As PPMS patients show diffuse and global myelin loss, the aim of this study was to evaluate the efficacy of whole-brain myelin water fraction (MWF) imaging in PPMS. Specifically, we sought to use full-brain anal...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Journal:
NeuroImage
Volume:
60
Issue:
1
Pages:
263-270
Publication date:
2012-03-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Source identifiers:
241990
Language:
English
Keywords:
Pubs id:
pubs:241990
UUID:
uuid:68980021-8f70-4ea7-b81a-b334adb3df15
Local pid:
pubs:241990
Deposit date:
2012-12-19

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