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Timing of hypoxia PET/CT imaging after 18F-fluoromisonidazole injection in non-small cell lung cancer patients

Abstract:

Positron emission tomography (PET)/computed tomography (CT) using the radiotracer 18F-Fluoromisonidazole (FMISO) has been widely employed to image tumour hypoxia and is of interest to help develop novel hypoxia modifiers and guide radiation treatment planning. Yet, the optimal post-injection (p.i.) timing of hypoxic imaging remains questionable. Therefore, we investigated the correlation between hypoxia-related quantitative values in FMISO-PET acquired at 2 and 4 h p.i. in patients wi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-022-26199-7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
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Name:
Cancer Research UK
Grant:
28684
C5255/A25069
16466
Publisher:
Springer
Journal:
Scientific Reports More from this journal
Volume:
12
Article number:
21746
Publication date:
2022-12-16
Acceptance date:
2022-12-12
DOI:
EISSN:
2045-2322
Language:
English
Keywords:
Pubs id:
1315553
Local pid:
pubs:1315553
Deposit date:
2022-12-19

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