Vaccinia virus intracellular mature virions contain only one lipid membrane.

Journal article

Vaccinia virus (VV) morphogenesis commences with the formation of lipid crescents that grow into spherical immature virus (IV) and then infectious intracellular mature virus (IMV) particles. Early studies proposed that the lipid crescents were synthesized de novo and matured into IMV particles that contained a single lipid bilayer (S. Dales and E. H. Mosbach, Virology 35:564-583, 1968), but a more recent study reported that the lipid crescent was derived from membranes of the intermediate com...

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Authors: Hollinshead, M; Vanderplasschen, A; Smith, G; Vaux, D

• Publication status: Published
• Journal: Journal of virology
• Volume: 73
• Issue: 2
• Pages: 1503-1517
• Publication date: 1999-02-01
• EISSN: 1098-5514
• ISSN: 0022-538X
• Language: English
• Keywords: Vaccinia virus; Hela Cells; Lipid Bilayers; Epoxy Resins; Virion; Humans; Microtomy; Myelin Sheath; Organelles; Viral Envelope Proteins; Virus Assembly