Journal article
The effect of changing somatostatin tone on the pituitary growth hormone and thyroid-stimulating hormone responses to their respective releasing factor stimuli.
- Abstract:
-
Somatostatin (SS) inhibits GH and TSH secretion, but its role in modulating their pulsatility is unclear. We studied GH and TSH responses to GH-releasing hormone (GHRH) and TRH stimulation upon a variable background infusion of saline, SS-(1-14) at 20 and 100 micrograms/m2.h, and oral pyridostigmine (30 and 60 mg) in six adult males. Basal GH levels were unaffected by SS-(1-14). Deconvolution analysis of serum GH values demonstrated that the pituitary responded to two GHRH stimuli 90 min apar...
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- Publication status:
- Published
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- Publisher copy:
- 10.1210/jc.75.2.453
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Bibliographic Details
- Journal:
- The Journal of clinical endocrinology and metabolism
- Volume:
- 75
- Issue:
- 2
- Pages:
- 453-458
- Publication date:
- 1992-08-05
- DOI:
- EISSN:
-
1945-7197
- ISSN:
-
0021-972X
- URN:
-
uuid:688f6da9-987f-4598-96f9-a857e0f788bb
- Source identifiers:
-
72720
- Local pid:
- pubs:72720
Item Description
Terms of use
- Copyright date:
- 1992
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