- Abstract:
-
BACKGROUND: Organ dysfunction and tissue hypoxia in severe falciparum malaria result from an imbalance between oxygen delivery and demand. In severe malaria, microvascular obstruction from parasite sequestration decreases oxygen delivery. However, host microvascular function (defined as the capacity to increase oxygen delivery in response to ischemia) and oxygen consumption have not been assessed. METHODS: We used near-infrared resonance spectroscopy to measure thenar muscle microvascular fun...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/infdis/jis692
-
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- Journal:
- The Journal of infectious diseases
- Volume:
- 207
- Issue:
- 3
- Pages:
- 528-536
- Publication date:
- 2013-02-05
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- URN:
-
uuid:6887ba13-9316-4a50-9900-d49fdc39d115
- Source identifiers:
-
363807
- Local pid:
- pubs:363807
- Copyright date:
- 2013
Journal article
Impaired skeletal muscle microvascular function and increased skeletal muscle oxygen consumption in severe falciparum malaria.
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