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Journal article

Impaired skeletal muscle microvascular function and increased skeletal muscle oxygen consumption in severe falciparum malaria.

Abstract:

BACKGROUND: Organ dysfunction and tissue hypoxia in severe falciparum malaria result from an imbalance between oxygen delivery and demand. In severe malaria, microvascular obstruction from parasite sequestration decreases oxygen delivery. However, host microvascular function (defined as the capacity to increase oxygen delivery in response to ischemia) and oxygen consumption have not been assessed. METHODS: We used near-infrared resonance spectroscopy to measure thenar muscle microvascular fun...

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Publication status:
Published

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Publisher copy:
10.1093/infdis/jis692

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Journal:
Journal of infectious diseases
Volume:
207
Issue:
3
Pages:
528-536
Publication date:
2013-02-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Source identifiers:
363807
Language:
English
Keywords:
Pubs id:
pubs:363807
UUID:
uuid:6887ba13-9316-4a50-9900-d49fdc39d115
Local pid:
pubs:363807
Deposit date:
2013-11-16

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