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Central nervous system infection diagnosis by next-generation sequencing: a glimpse into the future?

Abstract:
Japanese encephalitis virus was detected by deep sequencing for the first time in urine of a 16-year-old boy with encephalitis. Seroconversion and polymerase chain reaction analysis confirmed the metagenomics finding. Urine is useful for diagnosis of flaviviral encephalitis, whereas deep sequencing can be a panpathogen assay for the diagnosis of life-threatening infectious diseases.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/ofid/ofx046

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Publisher:
Oxford University Press Publisher's website
Journal:
Open Forum Infectious Diseases Journal website
Volume:
4
Issue:
2
Pages:
ofx046
Publication date:
2017-03-04
Acceptance date:
2017-03-03
DOI:
ISSN:
2328-8957
Pubs id:
pubs:695799
URN:
uri:68857faa-6552-4f43-85ed-5ac650b4db88
UUID:
uuid:68857faa-6552-4f43-85ed-5ac650b4db88
Local pid:
pubs:695799

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