Central nervous system infection diagnosis by next-generation sequencing: a glimpse into the future?
- Japanese encephalitis virus was detected by deep sequencing for the first time in urine of a 16-year-old boy with encephalitis. Seroconversion and polymerase chain reaction analysis confirmed the metagenomics finding. Urine is useful for diagnosis of flaviviral encephalitis, whereas deep sequencing can be a panpathogen assay for the diagnosis of life-threatening infectious diseases.
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- Peer reviewed
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- © Mai, et al 2017 Published by Oxford University Press on behalf of Infectious Diseases Society of America
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