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Journal article

Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease.

Abstract:

BACKGROUND: Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these mechanisms could be important effect modifiers. OBJECTIVE: Our goal was to assess interactions between exposure to air pollution and single nucleotide polymorphisms (SNPs) in the beta2-adrenergic receptor (ADRB2), glutathione S-transferase P1 (GSTP1), and tumor necrosis factor (TNF) genes for development of childhood allergic disease. METHOD...

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Publication status:
Published

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Publisher copy:
10.1289/ehp.11117

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Berglind, N More by this author
Zucchelli, M More by this author
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Journal:
Environmental health perspectives
Volume:
116
Issue:
8
Pages:
1077-1084
Publication date:
2008-08-05
DOI:
EISSN:
1552-9924
ISSN:
0091-6765
URN:
uuid:687fe0ca-84dc-4201-b1a1-6bc2ff19e534
Source identifiers:
7591
Local pid:
pubs:7591

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