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The role of epicardial adipose tissue in cardiac biology: classic concepts and emerging roles

Abstract:

Classic concepts about the role of epicardial adipose tissue (EpAT) in heart physiology include its role in cardiac metabolism, mechanical protection of coronaries, innervation and possibly cryoprotection of the heart too. Nevertheless, recent evidence has revealed that epicardial adipose tissue regulates multiple aspects of cardiac biology including myocardial redox state, intracellular Ca(2+) cycling, the electrophysiological and contractile properties of cardiomyocytes, cardiac fibrosis as...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1113/JP273049

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More from this funder
Funding agency for:
Antoniades, C
Grant:
NNF15CC0018486
More from this funder
Funding agency for:
Antoniades, C
Grant:
NNF15CC0018486
Publisher:
Wiley Publisher's website
Journal:
Journal of Physiology Journal website
Volume:
595
Issue:
12
Pages:
3907–3917
Publication date:
2017-03-13
Acceptance date:
2017-01-05
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Language:
English
Keywords:
Pubs id:
pubs:679965
UUID:
uuid:687c3456-6974-4302-b30d-2df1738d0b3a
Local pid:
pubs:679965
Source identifiers:
679965
Deposit date:
2017-03-20

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