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Analysis of spatial variation of nuclear morphology in tissue microenvironments

Abstract:

We present a study of the spatial variation of nuclear morphology of stromal and cancer-associated fibroblasts in the mouse mammary gland. The work is part of a framework being developed for the analysis of the tumor microenvironment in breast cancer. Recent research has uncovered the role of stromal cells in promoting tumor growth and progression. In specific, studies have indicated that stromal fibroblasts - formerly considered to be passive entities in the extra-cellular matrix - play an a...

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Publisher copy:
10.1109/ISBI.2010.5490233

Authors


Journal:
2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings More from this journal
Pages:
1293-1296
Publication date:
2010-01-01
DOI:
Language:
English
Keywords:
Pubs id:
pubs:439052
UUID:
uuid:687a5474-42b9-4e76-bc93-eb837c77739e
Local pid:
pubs:439052
Source identifiers:
439052
Deposit date:
2014-02-08

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