Cerebral blood flow sensitivity to CO2 measured with steady-state and Read's rebreathing methods.

Journal article

The ventilatory response to carbon dioxide (CO2) measured by the steady-state method is lower than that measured by Read's rebreathing method. A change in end-tidal P CO2 (PET CO2) results in a lower increment change in brain tissue P CO2 (Pt CO2) in the steady-state than with rebreathing: since Pt(CO2) determines the ventilatory response to CO2, the response is lower in the steady-state. If cerebral blood flow (CBF) responds to Pt CO2, the CBF-CO2 response should be lower in the steady-state...

Expand abstract

Authors: Pandit, J; Mohan, R; Paterson, N; Poulin, M

• Publication status: Published
• Journal: Respiratory physiology and neurobiology
• Volume: 137
• Issue: 1
• Pages: 1-10
• Publication date: 2003-08-01
• DOI: 10.1016/s1569-9048(03)00089-2
• EISSN: 1878-1519
• ISSN: 1569-9048
• Language: English
• Keywords: Hypercapnia; Respiration; Partial Pressure; Carbon Dioxide; Breath Tests; Respiratory Center; Oxygen; Ultrasonography, Doppler, Transcranial; Cerebrovascular Circulation; Humans; Tidal Volume