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Dynamics of polydisperse irreversible adsorption: a pharmacological example

Abstract:

Many drug delivery systems suffer from undesirable interactions with the host immune system. It has been experimentally established that covalent attachment (irreversible adsorption) of suitable macromolecules to the surface of the drug carrier can reduce such undesirable interactions. A fundamental understanding of the adsorption process is still lacking. In this paper, the classical random irreversible adsorption model is generalized to capture certain essential processes involved in pharma...

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Publication status:
Published

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Publisher copy:
10.1142/S0218202507002091

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Journal:
MATHEMATICAL MODELS and METHODS IN APPLIED SCIENCES More from this journal
Volume:
17
Issue:
5
Pages:
759-781
Publication date:
2006-01-31
DOI:
EISSN:
1793-6314
ISSN:
0218-2025
Language:
English
Keywords:
Pubs id:
pubs:17382
UUID:
uuid:6857ef1a-a4e5-45ce-923e-049ba1402d13
Local pid:
pubs:17382
Source identifiers:
17382
Deposit date:
2012-12-19

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