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The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis.

Abstract:

Patterns of genetic diversity within populations of human pathogens, shaped by the ecology of host-microbe interactions, contain important information about the epidemiological history of infectious disease. Exploiting this information, however, requires a systematic approach that distinguishes the genetic signal generated by epidemiological processes from the effects of other forces, such as recombination, mutation, and population history. Here, a variety of quantitative techniques were empl...

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Publication status:
Published

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Publisher copy:
10.1093/molbev/msi041

Authors


Jolley, KA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Maiden, MC More by this author
Journal:
Molecular biology and evolution
Volume:
22
Issue:
3
Pages:
562-569
Publication date:
2005-03-05
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
URN:
uuid:6840f207-86f9-41af-b530-effbc6585746
Source identifiers:
69637
Local pid:
pubs:69637

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