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Clinical impact of genetic aberrations in gastric MALT lymphoma: a comprehensive analysis using interphase fluorescence in situ hybridisation.

Abstract:

BACKGROUND AND AIMS: There is a need for genetic biomarkers to guide prognosis and management of gastric mucosa-associated lymphoid tissue (MALT) lymphomas. We assessed the incidence and clinical significance of the MALT lymphoma-associated genetic abnormalities t(11;18)/API2-MALT1, t(1;14)/BCL10-IGH, t(14;18)/IGH-MALT1, t(3;14)/FOXP1-IGH, and extra copies of MALT1 and FOXP1 in gastric MALT lymphomas from Japan. METHODS: The presence of translocations and copy number changes involving MALT1,...

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Publisher copy:
10.1136/gut.2007.123729

Authors


Nakamura, S More by this author
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Journal:
Gut
Volume:
56
Issue:
10
Pages:
1358-1363
Publication date:
2007-10-05
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
URN:
uuid:683d4ba3-2006-4e3d-a4ca-ed5497d606a2
Source identifiers:
246478
Local pid:
pubs:246478

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